Economic benefit from the optimization of citric acid production from rice straw through Plackett-Burman design and central composite design
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Date
2012Author
Hayder Khaleel, Qurban Ali
Mohamed Zulkali, Mohamed Daud
Zinah, Al-Azzawi
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An economic study was carried out to show the benefits of optimization during the production of
citric acid from rice straw as a substrate by solid-state fermentation (SSF) using Aspergillus niger. The
optimization procedure for the media components (NH4NO3, KH2PO4, MgSO4 , CuSO4 , ZnSO4, FeSO4 ,
and MnSO4) was carried out using Plackett-Burman design (PBD) for the screening and central composite
design (CCD) for the optimization. The results obtained from PBD indicated that NH4NO3, KH2PO4 ,
and MgSO4 were the most significant components that affected the citric acid production. The maximum
yield obtained by CCD was 50.23 g citric acid/kg rice straw. The rate of citric acid production by SSF after
the optimization indicated a profit of about 65% for SSF without any nutrient addition and of about 27%
for SSF without optimization.
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http://journals.tubitak.gov.tr/engineering/issues/muh-12-36-1/muh-36-1-7-1101-8.pdfhttp://dspace.unimap.edu.my/123456789/22965