Determination of the parameters in designing the drying chamber for Orthosiphon Stamineus

Abstract

Leaf of Orthosiphon stamineus was fermented or extracted with the distilled water and the extracts were subjected to qualitative and quantitative High Performance Liquid Chromatography (HPLC) analyses of the polyphenols, the most dominant chemical constituents in the leaf. An HPLC method was developed for the separation and determination of Rosmarinic acid (RA) in Orthosiphon stamineus. The separation system consisted of a C18 reversed-phase column, a gradient elution system of methanol/water containing orthophosphoric acid, and a photodiode array detector. The extraction with water extracts at 4 and 8 h gave a high yield of Rosmarinic Acid. There are literature review said that the concentration of active ingredient in the herbs may be lower than the dried herbs. The moisture content, drying rate, temperature, air circulation and drying time were controlled during the drying process since they can affect the drying process and the active compound in the herbs. Therefore, these parameters will be controlled and used to design the drying chamber for Orthosiphon stamineus.