dc.contributor.author | Killion, John | |
dc.contributor.author | Gonzalez, Nelly | |
dc.contributor.author | Geever, Luke | |
dc.contributor.author | Devine, Declan | |
dc.contributor.author | Kennedy, James | |
dc.contributor.author | Higginbotham, Clement L. | |
dc.date.accessioned | 2013-09-03T02:10:49Z | |
dc.date.available | 2013-09-03T02:10:49Z | |
dc.date.issued | 2012-06-18 | |
dc.identifier.citation | p. 1-8 | en_US |
dc.identifier.isbn | 978-967-5760-11-2 | |
dc.identifier.uri | http://dspace.unimap.edu.my/123456789/27877 | |
dc.description | The 2nd
International Malaysia-Ireland Joint
Symposium on Engineering, Science and Business 2012 (IMiEJS2012) jointly organized by Universiti Malaysia Perlis and Athlone Institute of Technology in collaboration with The Ministry of Higher Education (MOHE) Malaysia, Education Malaysia and Malaysia Postgraduates Student Association Ireland (MyPSI), 18th - 19th June 2012 at Putra World Trade Center (PWTC), Kuala Lumpur, Malaysia. | en_US |
dc.description.abstract | The current gold standard treatment for bone defects are biological grafts. Due to the
inherent disadvantages for these biological grafts, a new synthetic alternative are being sought.
Tissue engineering has shown great potential to replace the current treatments, due to its ability to
provide structural support to the defect while promoting cellular attachment, proliferation and
migration to help the formation new bone tissue. In this study, novel biocomposites of polyethylene
glycol dimethacrylate (PEGDMA) and hydroxyapatite (HaP) were prepared via
photopolymerisation. The objective of this study was to understand the effects of varying
hydroxyapatite concentration had on the mechanical and thermal properties of the resultant
biocomposite. The prepared hydrogel based composites were characterised by compression testing,
gel fraction, differential scanning calorimetry (DSC) and swelling studies. Compression strength
were tailored by very hydroxyapatite concentration (5 wt%-17.5 wt%). For example, variation in
HaP concentration (A0-A17.5) resulted in an increase in Young’s modulus from 5.41 MPa to 5.89
MPa. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Universiti Malaysia Perlis (UniMAP) | en_US |
dc.relation.ispartofseries | Proceedings of the The 2nd International Malaysia-Ireland Joint Symposium on Engineering, Science and Business 2012 (IMiEJS2012); | |
dc.subject | Hydroxyapatite | en_US |
dc.subject | Polyethylene glycol | en_US |
dc.subject | Mechanical properties | en_US |
dc.title | Synthesis and characterisation of hydrogel based composites for bone regeneration | en_US |
dc.type | Working Paper | en_US |
dc.contributor.url | jkillion@research.ait.ie | en_US |
dc.contributor.url | magargo7@etsid.upv.es | en_US |