Antibacterial And Wound Healing Properties Of Curcuma Longa
Abstract
Wounds could become the major cause of physical disabilities. In order to heal successfully wounds must undergo several processes. However, the healing process of wound could be delayed in the presence of antimicrobial infections. Therefore, clinicians use many methods
to prevent the wound infection including the use of synthetic drugs such as antibiotic and
antiseptic agent. Traditional use of C. longa has mentioned its ability in wound treatment.
This research was conducted to study the antimicrobial and wound healing properties of C.
longa rhizomes. The extract of C. longa rhizome was prepared by using maceration
method. Phytochemical test was conducted to identify the bioactive compound that exists
in C. longa such as alkaloid, saponin, tannin and many more. The antibacterial properties of
C. longa was studied by using disc diffusion method. The methanolic extract of the plant
rhizome was tested against three types of bacteria which are Bacillus cereus, Streptococcus
phyogens and Salmonella. Different concentration of extract which were 50, 100 and 200
mg/ml was used to identify the minimum inhibitory zone of the bacteria. Then, the wound
healing abilities of C. longa was studied by using excision wound healing model. Excision
wound healing model was conducted towards mice. The area of wound contraction was
measured day by day until the wound heals completely. The tested result was compared
with untreated sample to observe its effectivity to heal wound.