Browsing Research & Innovations by Subject "Hot melt extrusion technology"
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Improved solubility of hydrophobic drugs using hot melt extrusion technology
(Universiti Malaysia Perlis (UniMAP), 2012-06-18)It is estimated that about 40% of all new chemical entities have poor bioavailability because of low aqueous solubility. This percentage still increases due to combinatorial chemistry and the impact of lipophilic receptors1. ...