Nanogap Dielectric Capacitor for Label Free Bio-Molecules Detection

Abstract

This research demonstrating that nanogap biosensor was fabricated by standard CMOS technologies function as extremely sensitive and selective biosensor for biomolecular detection and medical diagnostic application using label-free detection technique. The difference in dielectric properties between single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) permits use of capacitance measurements to detect DNA hybridization which is time saving and cost effective.