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Title: | A study of Inhaled Pharmaceutical Aerosol (IPA) flow characteristic with various types of fan design in metered dose inhaler |
Authors: | Md Tasyrif, Abdul Rahman Ahmad Faizal A.S., Fathinul-Syahir Sazali, Yaacob Hazlinda, Razali Fauziah, Mat Nur Saifullah Mohd Sofian |
Keywords: | Metered Dose Inhaler (MDI) Inhaled Pharmaceutical Computational Fluid Dynamic (CFD) Engineering fluid dynamics (EFD) Hub tip ratio Axial flow fan Aerosols Aerosol therapy |
Issue Date: | 11-Oct-2009 |
Publisher: | Universiti Malaysia Perlis |
Citation: | p. 1D 1 - 1D 7 |
Series/Report no.: | Proceeding of International Conference on Applications and Design in Mechanical Engineering 2009 (iCADME 2009) |
Abstract: | Metered Dose Inhalers (MDI) is used to prevent and relieve the symptoms and progression of certain diseases (asthma, chronic obstructive pulmonary disease, cystic fibrosis and bronchiectasis) by delivering the inhaled pharmaceutical aerosols (IPA) to the desired area. The MDI is easily can be placed in a pocket or purse and ready to be used instantly and these are the reasons why it is used widely. The spacer is used to avoid deposition of most IPA on the mouth throat area whereby it promotes the expansion and mixing of the IPA before it is inhaled. However, the IPA inhaling efficiency using MDI is relatively low compared to other methods. A study on the effect of various types of fan design will carry out to understand their effects on the IPA fluid dynamics characteristics. The Computational Fluid Dynamics (CFD) software was used to analyze the IPA flow pattern inside the spacer. The expected results should show that the effective fan design will generate expected characteristics of air flow inside the spacer and will give a better delivery of the IPA through MDI spacer. |
Description: | Organized by School of Mechatronic Engineering (UniMAP) & co-organized by The Institution of Engineering Malaysia (IEM), 11th - 13th October 2009 at Batu Feringhi, Penang Malaysia. |
URI: | http://dspace.unimap.edu.my/123456789/7168 |
Appears in Collections: | Conference Papers Sazali Yaacob, Prof. Dr. Ahmad Faizal Salleh, Assoc. Prof. Ir. Dr. |
Files in This Item:
File | Description | Size | Format | |
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A study of Inhaled Pharmaceutical Aerosol (IPA) | 268.78 kB | Adobe PDF | View/Open |
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