Classification of blasts in acute leukemia blood samples using k-nearest neighbour

Abstract

The k-nearest neighbor (k-NN) is a traditional method and one of the simplest methods for classification problems. Even so, results obtained through k-NN had been promising in many different fields. Therefore, this paper presents the study on blasts classifying in acute leukemia into two major forms which are acute myelogenous leukemia (AML) and acute lymphocytic leukemia (ALL) by using k-NN. 12 main features that represent size, color-based and shape were extracted from acute leukemia blood images. The k values and distance metric of k-NN were tested in order to find suitable parameters to be applied in the method of classifying the blasts. Results show that by having k 4 and applying cosine distance metric, the accuracy obtained could reach up to 80%. Thus, k-NN is applicable in the classification problem.