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dc.contributor.authorSyed Muhammad, Usman Ali, Dr.-
dc.contributor.authorZafar Hussain, Ibupoto-
dc.contributor.authorMuhammad, Kashif-
dc.contributor.authorUda, Hashim, Prof. Dr.-
dc.contributor.authorWillander, Magnus-
dc.date.accessioned2013-03-07T07:51:44Z-
dc.date.available2013-03-07T07:51:44Z-
dc.date.issued2012-03-
dc.identifier.citationSensors, vol. 12(3), 2012, pages 2787-2797en_US
dc.identifier.issn1424-8220-
dc.identifier.urihttp://www.mdpi.com/1424-8220/12/3/2787-
dc.identifier.urihttp://dspace.unimap.edu.my/123456789/23982-
dc.descriptionLink to publisher's homepage at http://www.mdpi.com/en_US
dc.description.abstractIn the present work zinc oxide nanoflakes (ZnO-NF) structures with a wall thickness around 50 to 100 nm were synthesized on a gold coated glass substrate using a low temperature hydrothermal method. The enzyme uricase was electrostatically immobilized in conjunction with Nafion membrane on the surface of well oriented ZnO-NFs, resulting in a sensitive, selective, stable and reproducible uric acid sensor. The electrochemical response of the ZnO-NF-based sensor vs. a Ag/AgCl reference electrode was found to be linear over a relatively wide logarithmic concentration range (500 nM to 1.5 mM). In addition, the ZnO-NF structures demonstrate vast surface area that allow high enzyme loading which results provided a higher sensitivity. The proposed ZnO-NF array-based sensor exhibited a high sensitivity of ~66 mV/ decade in test electrolyte solutions of uric acid, with fast response time. The sensor response was unaffected by normal concentrations of common interferents such as ascorbic acid, glucose, and urea.en_US
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.subjectZnO nanoflakes (ZnO-NFs)en_US
dc.subjectPotentiometric nanosensoren_US
dc.subjectUricaseen_US
dc.subjectNafion® membraneen_US
dc.titleA potentiometric indirect uric acid sensor based on ZnO nanoflakes and immobilized uricaseen_US
dc.typeArticleen_US
dc.contributor.urlsyeal@itn.liu.seen_US
dc.contributor.urlzafar.hussain.ibupoto@liu.seen_US
dc.contributor.urlkashif_bme@yahoo.comen_US
dc.contributor.urluda@unimap.edu.myen_US
dc.contributor.urlmagwi@itn.liu.seen_US
Appears in Collections:Institute of Nano Electronic Engineering (INEE) (Articles)
Uda Hashim, Prof. Ts. Dr.

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