DSpace
 

iRepository at Perpustakaan UniMAP >
The Library >
Conference Papers >

Please use this identifier to cite or link to this item: http://dspace.unimap.edu.my:80/dspace/handle/123456789/20845

Title: Neural network based phylogenetic analysis
Authors: Halgaswaththa, Thilini
Atukorale, Ajantha S.
Jayawardena, Mahen
Weerasena, Jagathpriya
???metadata.dc.contributor.url???: mcj@ucsc.cmb.ac.lk
jagath@ibmbb.cmb.ac.lk
Keywords: Phylogenetics;Probabilistic neural network;Trigram method;Feed forward neural networks
Issue Date: 27-Feb-2012
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Citation: p. 155-160
Series/Report no.: Proceedings of the International Conference on Biomedical Engineering (ICoBE 2012)
Abstract: Phylogeny is the primary tool used to understand the evolutionary relationship between various taxonomic groups. If someone finds an unknown bone fragment it is important to first identify which “class of animal” that fragment may relate to. The standard way would be to extract DNA, amplify and sequence a conserved region and construct a phylogenetic tree and then understand the Class to which it belongs. But this method involves various tasks such as multiple sequences alignment and constructing dendrogram by distance, parsimony or Bayesian methods, which requires considerable time and effort. In this research we implemented a probabilistic neural network to understand the possible class of animal of an unknown DNA sequence without using the phylogenetic tree approach. To achieve this target we used 90 Transferring sequence and 400 sequences of NADH dehydrogenase subunit I coding region of Mitochondrial DNA as data sets. The neural network was trained using the inputs created based on codon count extracted from the DNA sequences using tri gram method. The performance of the neural network based analysis was compared with phylogenetic analysis and the accuracy of the probabilistic and feed forward neural network approaches were also compared. Results revealed that the new approach performed better than the standard phylogenetic approach.
Description: Link to publisher's homepage at http://ieeexplore.ieee.org/
URI: http://ezproxy.unimap.edu.my:2080/stamp/stamp.jsp?tp=&arnumber=6178974
http://hdl.handle.net/123456789/20845
ISBN: 978-145771989-9
Appears in Collections:Conference Papers

Files in This Item:

File Description SizeFormat
2C4.pdfAccess is limited to UniMAP community721.85 kBAdobe PDFView/Open
View Statistics

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

 

Valid XHTML 1.0! Perpustakaan Tuanku syed Faizuddin Putra, Kampus Pauh Putra, Universiti Malaysia Perlis, 02600, Arau Perlis
TEL: +604-9885420 | FAX: +604-9885405 | EMAIL: rujukan@unimap.edu.my Feedback